Precision Diagnostics
& Variant Resolution
Empowering clinical geneticists and oncologists with unparalleled genomic clarity. We provide automated host-pathogen genomic reports (powered by our v@pp platform) and offer Thailand’s first Variant Resolution Service. We utilize advanced CRISPR mutagenesis and RNA-Seq to functionally validate Variants of Uncertain Significance (VUS), transforming unknown mutations into actionable diagnostic targets.
Genomic Medicine Service
Platform
Empowering Thailand’s healthcare system through a comprehensive Genomic Medicine Service Platform. By combining high-performance computing (HPC) with advanced data management and processing, this ecosystem delivers the v@pp platform-a centralized tool that annotates and prioritizes variants for rare disease and cancer patients. This infrastructure ensures equitable access to life-saving genomic medicine for all.
Health Data Science
Platform
Driving medical innovation through a secure Health Data Science Platform. This ecosystem transforms raw health data into research-ready assets while maintaining strict compliance with Thailand’s PDPA. By balancing rigorous data security with accessibility, it empowers researchers to safely utilize healthcare data for scientific breakthroughs.
Pharmacogenomic
Analysis Service
Our Pharmacogenomic Analysis Service processes raw sequencing data—FASTQ or VCF—into structured pharmacogenomic information. The analysis covers a curated set of pharmacogenes, including clinically relevant HLA genes, to identify genetic variants associated with drug metabolism and response.
Clients receive a comprehensive PGx report including allele-level genotype results and corresponding drug–gene guideline information based on CPIC recommendations, with coverage for over 50 medications across multiple therapeutic areas. These outputs provide healthcare professionals and researchers with reliable genomic information for further evaluation.
For research-oriented projects, we also offer functional annotation of SNPs and short indels across more than 3,000 pharmacogenes to support exploration of variant impact and biological relevance.
Customized report formats and tailored analyses are available to meet specific project or clinical research needs. All deliverables are provided as secure scientific technical reports intended for use by qualified professionals as supporting information (non-medical interpretation)
Transcriptome
Analysis Service
Targeted transcriptome analysis service enabling patient-specific gene expression profiling to guide precision diagnosis, risk stratification, and tailored therapeutic decisions in modern precision medicine.
DNA
Methylation
Our DNA methylation analysis service supports clients in exploring methylation markers across multiple leading platforms, including:
• cfDNA methylation profiling using the Twist Human Methylome Panel for liquid biopsy and early-detection applications.
• Tumor methylation profiling using the Illumina methylation array (EPIC/EPIC-v2 and others) for tumor classification, biomarker discovery, and clinical research.
• 5-base HiFi long-read methylation analysis enabling simultaneous detection of CpG, 5-mC, and 5-hmC signals directly from Pacific Biosciences HiFi sequencing.
Our service delivers comprehensive methylation data analysis—from preprocessing and QC to differential methylation analysis, clustering, biomarker discovery, and integrative multi-omics visualization. This supports clients aiming to identify new screening markers, conduct in-depth biological research, or enhance the value of long-read (HiFi) datasets with high-resolution methylation insights.
